Discussion about this post

User's avatar
A Gentleman Of Letters's avatar

I am all for stopping the mass application of glyphosate given the International Agency for Research on Cancer classified glyphosate as a possible carcinogen. However the US Government is permitting & promoting diquat as the replacement.

=====

Diquat is thought to be a neurotoxin, carcinogen and linked to Parkinson’s disease. An October analysis of EPA data by the Friends of the Earth … found it is … 200 times more toxic than glyphosate in terms of chronic exposure.

“From a human health perspective, this stuff is quite a bit nastier than glyphosate so we’re seeing a regrettable substitution, and the ineffective regulatory structure is allowing it,” said Nathan Donley, Science Director with the Center For Biological Diversity.

The new review focuses … on the multiple ways in which diquat damages organs and gut bacteria, including by reducing the level of proteins that are key pieces of the gut lining allow[ing] toxins and pathogens to move from the stomach into the bloodstream, and trigger inflammation.

Meanwhile, diquat can [also] inhibit the production of beneficial bacteria that maintain the gut lining inhibit[ing] the absorption of nutrients and energy metabolism.

The research … scrutinizes how the substance harms the kidneys, lungs and liver. Diquat “causes irreversible structural and functional damage to the kidneys” because it can destroy kidney cells’ membranes and interfere with cell signals.

The effects on the liver are similar, and the ingredient causes the production of proteins that inflame the organ.

It seems to attack the lungs by triggering inflammation that damages the organ. The inflammation caused by diquat may cause multiple organ dysfunction syndrome, a scenario in which organ systems begin to fail.

Despite the risks amid a rise in diquat’s use, the EPA is not reviewing the chemical, and even non-profits that push for tighter pesticide regulations have largely focused their attention elsewhere.

Donley said that was … because US pesticide regulations are so weak that advocates are tied up with battles over ingredients like glyphosate, paraquat and chlorpyrifos – substances that are banned elsewhere but still widely used [in the US.]

“Other countries have banned diquat, but in the US we’re still fighting the fights that Europe won 20 years ago and that really says a lot about the sad and sorry state of pesticides in the US.”

Advocates have accused the EPA of being captured by industry.

Donley said US pesticide laws were so weak that it was difficult for the agency to ban ingredients, even if the will exists [eg.], the agency banned chlorpyrifos in 2022, but a court overturned the decision after [the] industry sued.

The EPA’s pesticides office seems to have a philosophy that states … toxic pesticides are a “necessary evil.”

“When you approach an issue from that lens there’s only so much you will do,” [Donley] said.

=====

Excerpts taken from.

Weedkiller ingredient widely used in US can damage organs and gut bacteria. The Guardian. T Perkins. 6-Jul-25.

https://www.theguardian.com/environment/2025/jul/06/weedkiller-diquat-organ-damage-study?CMP=share_btn_url

Expand full comment

No posts